产品货号：
Z24296
中文名称：
PRNP抗体
英文名称：
Anti-PRNP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PRNP Antibody |
| 指标别名 | prion protein;ASCR;AltPrP;CD230;CJD;GSS;KURU;PRIP;PrP;PrP27-30;PrP33-35C;PrPc;p27-30;PRNP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PRNP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human PRNP(144-160aa DYEDRYYRENMHRYPNQ). |
| 实际分子量 | 28KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRNP(prion protein),also known as CD230 and PRP,is a protein that in humans is encoded by the PRNP gene.The major prion protein is expressed in the brain and several other tissues.Expression is most predominant in the nervous system but occurs in many other tissues throughout the body.Puckett et al.(1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene,which might serve as a useful marker for the pter-p12 region of chromosome 20.PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease,bovine spongiform encephalopathy,and kuru.PRNP is highly conserved through mammals,lending credence to application of conclusions from test animals such as mice.Comparison between primates is especially similar,ranging from 92.9～99.6% similarity in amino acid sequences. |
| Uniprot ID | P04156 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | prion protein |
| 蛋白名全称 | Major prion protein(PrP) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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